Application of a screening test for antibody the hepatitis B core antigen.
نویسندگان
چکیده
منابع مشابه
Application of a screening test for antibody the hepatitis B core antigen.
Hepatitis B core antigen (HBcAg) was prepared from human liver tissue and used in an immunoelectro-osmophoresis screening test to detect antibody to HBcAg (anti-HBc) in patients with evidence of liver disease and in blood donors. With the exception of two immunosuppressed HBsAg carriers, anti-HBc was found in all cases of hepatitis B infection even when HBsAg was detectable only by radioimmunoa...
متن کاملThe value of screening blood donors for antibody to hepatitis B core antigen.
Rapid counter-immunoelectrophoresis (CIE) and radioimmunoassay (RIA) methods for detecting antibody to hepatitis B core antigen (anti-HBc) were used to screen nearly 8000 blood donors, including 919 prisoners. The prevalence of anti-HBc in prisoner donors (3.4%) was significantly higher than that in other donors (0.7%). The three HBsAg positive donors in the series were all anti-HBc positive an...
متن کاملRoutine use of counter-immunoelectrophoresis test for detecting antibody to hepatitis B virus core antigen.
Tests by counter-immunoelectrophoresis for antibody to hepatitis B core antigen (anti-HBc) were introduced into a routine testing programme for evidence of hepatitis B virus infection. Samples tested for anti-HBc were selected on the basis of the results of tests for HBsAg and clinical details. The sensitivity and specificity of the test were assessed and correlations made with the presence of ...
متن کاملSignificance of Hepatitis B Core Antibody as the Only Marker of Hepatitis B Virus Infection in High Risk Patients
Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...
متن کاملhepatitis B surface antigen . Donor screening for antibody to
The preparations obtained by this method present the cells in random orientation, so that the profiles seen on electron microscopy fulfil the first criterion for morphometric analysis; quantitative studies can therefore be made of morphological changes that take place during the maturation of monocytes into macrophages. Reports have indicated that mononuclear phagocyte maturation is disordered ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1977
ISSN: 0021-9746
DOI: 10.1136/jcp.30.8.709